Research Areas

• Mouse magnetic resonance imaging (MRI)
• Telemetry and calorimetry
• Cre-lines
• Cryopreservation/ in vitro fertilization/ICS

Erwin WAGNER, IMP
Josef PENNINGER, IMBA
Mathias MÜLLER, Biomodels Austria
Thomas RÜLICKE, Biomodels Austria

• Biochemical analysis of the RNAi pathway
  Javier MARTINEZ, IMBA
• Genetical analysis of the RNAi pathway
  Barry DICKSON, IMP
• RNAi in HeLa cells
  Jan-Michael PETERS, IMP

• Generation of genetically modified mice
• Basic and advanced phenotyping of new mouse mutants
• Archiving and rederivation of mouse mutants
• Generation of transgenic animals by targeted transgenesis via  Restriction-Enzyme-Mediated Integration (REMI)

Mathias MÜLLER, Biomodels Austria
Thomas RÜLICKE, Biomodels Austria

• Tetraploid Mouse Technology
  Erwin WAGNER, IMP
• Establishment of new systems for fast and efficient targeted transgenesis
  Maria SIBILIA, Medical University
• Tet ON/OFF inducible gene expression and homologous chromosome inactivation in ES cells and tetraploid mice
  Anton WUTZ, IMP
• in vivo RNAi knock-down experiments
  Josef PENNINGER, IMBA